North Queensland's finals hopes are in jeopardy after Brisbane outclassed their fierce rivals 20-10 at a sold-out 1300SMILES Stadium.
A hamstring injury on the halftime siren to star fullback Darius Boyd put a major dampener on Brisbane's polished display but a dominant first 40 minutes from the visitors was enough to leave their Queensland counterparts' season in limbo.
Three unanswered first half tries down the left flank did the damage for Brisbane, with the Cowboys now needing either a Penrith win over Manly at Lottoland on Friday, or a Bulldogs upset over the Dragons on Sunday to sneak in to the eight.
The Broncos almost jumped their northern neighbours with an early try when hulking forward Josh McGuire was held up over the line, as both sides traded half chances in the opening ten minutes.
Anthony Milford was proving to be a real handful for the North Queensland defence and after collecting his own grubber he found James Roberts who then offloaded to Matt Gillett - the second rower cantering 20m to score the game's opening try.