They may sport one of the silliest uniforms at the opening ceremony with their Ralph Lauren berets - perhaps they were made when Paris was favourite to host the 2012 Games - but there is unlikely to be any laughing from the rest of the world once the US team gets into action.
China forced them off the top of the medal table in Beijing for the first time since 1992, but they will almost certainly regain it in London. The United States' record in recent Games has been astonishingly consistent. Apart from a spike offered by hosting the Atlanta Games in 1996, they have won 36 or 37 gold medals at each of the past six Games.
Carl Lewis describes England as a home from home for the team, so expect to see big numbers.
The bulk of America's gold rush will come in the Aquatics Centre.
The swimmers have provided on average a third of the total number of golds over recent Games - the phenomenon that is Michael Phelps collected a quarter all on his own in Beijing.