Jason Eaton, Romana Graham and Victor Vito celebrated as La Rochelle downed Toulouse, who fielded Carl Axtens, Joe Tekori and Luke McAlister, 25-19.
Simon Hickey kicked three goals for Bordeaux-Begles in their narrow 24-22 victory over Grenoble. Loose forwards Luke Braid, Hugh Chalmers and Joe Edwards all took the field for the victors, while Grenoble fielded Rory Grice, Nigel Hunt and Steven Setephano.
A try to lock Taisina Tuifua could not prevent Lyon, with Mike Harris, Josh Bekhuis, Ti'i Paulo and Toby Arnold also in the ranks, from losing 25-20 at Montpellier.
David Smith's Castres beat Brive 32-13. Bottom-placed Bayonne, with Tom Donnelly at lock, tipped over leaders Clermont. Benson Stanley scored a try off the bench, while Hosea Gear entered the fray off the pine for Les Jaunards.
Ma'a Nonu's Toulon, in a game that has just finished, defeated Aled de Malmanche's Stade Francais 31-12. Nonu scored a second half try.
Several New Zealanders were rested from the weekend's Anglo-Welsh Cup fixtures.
Jack Umaga, however, scored two tries off the bench for Wasps in their big 62-10 victory over Worcester, while Samu Vunisa's Saracens, missing Sean Maitland on Scotland duty, beat Newcastle Falcons 29-18. Winston Stanley and George Naoupu featured in Harlequins' 15-12 win over Ospreys, Quins' tune-up for Thursday morning's clash with the Maori All Blacks.
Dan Bowden's Bath crashed 44-21 to Scarlets, promoting Bath director of rugby Todd Blackadder to tell media his side "are much better than that."
Halfback Jono Kitto was a replacement in Leicester Tigers' 42-3 thrashing of the Dragons.
Northampton Saints, with James Wilson and Michael Paterson in the mix, edged Joe Latta's Gloucester 19-13, while Mark Sorenson's Bristol saw off Sale Sharks 26-11.
Prop Halani Aulika scored a try for the Sharks, while Johnny Leota, TJ Ioane and Sam Tuitupou all turned out for the vanquished.