Opening bowler Josh Hazlewood struck with the last ball before lunch to give Australia a slight early advantage in the Boxing Day Test.
Pakistan were 60-2 after winning the toss, but Australian captain Steve Smith ended the session with a low, finger-tip catch at second slip to dismiss #3 batsman Babar Azam for 23.
Azhar Ali was unbeaten on 26, while the introduction of spinner Nathan Lyon into the attack after less than an hour of play paid immediate dividends, when he dismissed Sami Aslam for nine.
Rain was forecast and conditions were gloomy, with the MCG lights on at noon.
Thanks to one of the locals, it was already an eventful last over of the morning session even before Babar's dismissal.