Defender Gerard Pique, who left hospital just two days earlier after a bash to the head during Barcelona's Champions League semi-final defeat to Chelsea, praised his departing coach.
"Many thanks Pep for giving us so much," he wrote on his Twitter account.
"Four years full of victories, of good times and above all lessons in football."
Only on Monday, the 25-year-old Pique had said he was convinced Guardiola would stay on as coach because of his love for the club and the profession.
However the 41-year-old coach announced Friday he was bringing his four-year reign over one of the greatest eras in club football to an end.
"Four years is an eternity as coach of Barca. Time wears everything down, I feel drained and I need to replenish," said Guardiola, who cited exhaustion as the reason for his departure.
"I cannot replenish if I coach again immediately, I don't want to."
Barcelona president Sandro Rosell appointed Francesc "Tito" Vilanova, a former Barcelona player and Guardiola's assistant for the past four years, as the new coach.
Cesc Fabregas, who returned last year to childhood club Barcelona from Arsenal, said on Twitter: "Even though I was only with him for one year it felt like a lot more. For me Pep was my hero as a kid."
The Spain international gave a vote of confidence to Vilanova, who came through Barcelona's youth ranks as a player before joining other sides, rejoining the Catalans as a youth coach in 2007.
"For Tito, I wish the best in this new opportunity that football has given to him. We were together when I was a kid," Fabregas said.
Team-mates piled on the gratitude from their Twitter accounts.
"You have shown us the way," captain Carles Puyol wrote.
"Today the coach gave us the news and I just want to say thanks to him and to his team for these years," said Andres Iniesta.
"A sad day for me because of the decision taken by Pep, who has always treated us like his children," said Daniel Alves.
Former players also regretted Pep's departure.
"A Barca legend is going, the last of the Mohicans of the Cruyff era," wrote Bulgarian retired Barcelona player Hristo Stoichkov, referring to legendary Barca coach Johan Cruyff's "Dream Team" of the 1990s.
-AAP
