The decision by Arsenal manager Unai Emery to withdraw captain Granit Xhaka in the second half was initially greeted by large cheers.
They turned to jeers as Xhaka took his time to leave the field despite the score being level.
Xhaka reacted by waving his arms, cupping his ears and seemingly mouthing a profanity twice as he pushed away a handshake from Emery. Xhaka took off his shirt and headed straight down the tunnel.
It had started so well, with goals in the opening nine minutes.
Arsenal defensive duo Sokratis Papastathopoulos and David Luiz scored inside 106 seconds.
But it started to go wrong in the 32nd minute when Luka Milivojevic netted a penalty that was awarded after a VAR review. Palace winger Wilfried Zaha had initially been booked for diving.
"I didn't understand the referee and VAR reaction," Emery said. "For me there is no confusion. It is not a good decision."
Jordan Ayew's fourth goal in eight games brought Palace level before further VAR drama as Sokratis was denied a late winner when the review spotted a foul by Calum Chambers moments earlier.
Liverpool recovery
Liverpool's breakthrough on its way to a sixth European Cup by beating Tottenham in June came when Mousa Sissoko handled after 22 seconds to concede a penalty. Redemption came after 148 days for the French midfielder, and almost as quickly. Sissoko launched a counterattack that was completed by Son Heung-min hitting the bar and Tottenham striker Harry Kane heading in the rebound after 47 seconds.
But Liverpool captain Jordan Henderson volleyed in the equaliser seven minutes into the second half.
And Mohamed Salah, who netted the early penalty in the Champions League final, was on target again from the spot after Serge Aurier fouled Sadio Mane.
Liverpool, which was held by Manchester United last weekend, has 28 points from a possible 30 as it chases a first title since 1990. Jurgen Klopp's side is six points ahead of Manchester City.
United double
For the first time since the opening weekend victory over Chelsea, United scored more than once in a league game.
United broke the deadlock through Scott McTominay's low drive and thus became the first club to score 2000 Premier League goals.
The visitors were then awarded a penalty after a VAR review in the 28th minute, only for Tim Krul to save Marcus Rashford's effort. The forward made up for it moments later to get his 50th United goal.
United missed its second penalty before halftime when Anthony Martial was denied as Krul again guessed correctly to keep his side in the game.
It was 3-0 in the 73rd as Martial made up for his miss before Norwich pulled one back in the 88th through halftime substitute Onel Hernandez who became the first Cuban goalscorer in the Premier League.
Newcastle denied win
Wolverhampton, playing its 20th game of the season due to Europa League commitments, trailed to Jamaal Lascelles' first-half header for Newcastle. But the visitors dominated the second half and got their reward when Jonny levelled from close range in the 73rd minute after goalkeeper Martin Dúbravka palmed Matt Doherty's cross into his path.
Newcastle had Sean Longstaff sent off in the 82nd minute.
- AP