Chris Wood will take a well deserved break after his Burnley exploits, while Winston Reid and Ryan Thomas are both injured.
Senior players Marco Rojas, Michael McGlinchey, Tommy Smith and Themi Tzimopoulos will also miss the tournament, which involves Chinese Taipei, Kenya and the host nation.
It's also believed that Kosta Barbarouses and Jeremy Brockie will also be absent.
The rest of New Zealand's Major League Soccer contingent — including Deklan Wynne, Kip Colvey and Bill Tuiloma — won't be named, while Stefan Marinovic is out with injury.
Phoenix defender Cacace will be selected, completing a fairytale rise for the teenager, who only made his A League debut in February.
Another new face — and bolt from the blue — will be Noah Billingsley. He wasn't called up in the previous cycle, even though former coach Anthony Hudson cast the net far and wide.
The 20-year-old has been at University of California in Santa Barbara since 2015, the alma mater of Tony Lochhead and Michael Boxall.
There will be a large contingent of Phoenix players, with Alex Rufer, Cacace, Tom Doyle and Sarpreet Singh, as well as recently departed midfielder Matt Ridenton.
However Monty Patterson has been overlooked.
Niko Kirwan, who was in the squad for March, hasn't made the cut this time, while Henry Cameron, who tore his ACL on his All Whites debut in 2015, is set to return to the fold.
It's expected to be a squad heavy on British-based players, will up to seven players out of the United Kingdom.
The goalkeeping situation is intriguing, with Nik Tzanev, Max Crocombe and Michael Woud expected to be named again, after being called up in March.
Tzanev played two games at the 2015 Under-20 World Cup — against Myanmar and Portugal — then went off the radar for a while, before getting a deal at Wimbledon in League One in May last year, where he has been playing youth team football.
Crocombe has bounced around the lower leagues.
He moved to Salford FC, who play in the sixth tier of English football, in July last year.
Woud has been part of Sunderland's youth set up since July 2016.
It means there will be no room for Oliver Sail — who played four games for the Phoenix at the end of this season — or former Oly-Whites keeper Scott Basalaj, who was outstanding for Team Wellington last season.