In what is a World Cup year, keeping an eye on which international players receive rest will also be crucial.
In a new feature for this game, you can make trades within your team right up until kickoff of the match each player is involved in. So if Dan Carter is injured in a pre-match warm-up, there's still time to trade him out for Colin Slade if you have a spare trade available.
2.Budget, budget, budget
You'll have a fantasy budget of $2 million to select your squad and you may spend that amount as you see fit, with no limit put on the number you can select from each team.
You may want to monitor the latest news fairly carefully, as well as the player stats (published weekly online and in the Stats Centre) to ensure players are on form/not nursing injury etc.
Remember too there are some excellent players who aren't 'big names' that will provide great value for money.
Select your captain carefully as they are worth double points. Your vice captain will take his place if they do not play in the fixture.
3. 2014 statistics
One of the best ways to gauge a player's worth is to look back at how they performed last season.
Where available, we display the average score each player recorded in 2014 beside their name when selecting your squad, so use this information wisely.
Another interesting result of analysing last year's statistics is the make-up of an All-Star squad - made from the best players at each position based on 2014 fantasy performances.
Of the 15 players, six were from NZ franchises, seven were Australia-based and just two hailed from South Africa. Again, act accordingly.
4. Team announcements
Players get injured in training, get cited for on and off field activity or are put on the bench or dropped for a plethora of reasons.
If you get a chance, remember to check final team lists prior to the kickoff of each game to make any last minute changes to your team.
Players confirmed missing in Round 1:
Blues:
Keven Mealamu
George Moala
Patrick Tuipulotu
Blake Gibson
Dan Bowden
Bulls:
Dean Greyling
Akona Ndungane
Marcel van der Merwe
Flip van der Merwe
Adriaan Strauss
Chiefs:
Aaron Cruden
Liam Messam
Brodie Retallick
Crusaders:
Kieran Read
Sam Whitelock
Israel Dagg
Nemani Nadolo
Willi Heinz
Andy Ellis
Force:
Matt Hodgson
Nick Cummins
Hurricanes:
Ma'a Nonu
Jeremy Thrush
Nehe Milner-Skudder
John Schwalger
Rebels:
Shota Horie
Tom Kingston
Reds:
Quade Cooper
Anthony Fainga'a
Greg Holmes
Dave McDuling
Ed Quirk
Beau Robinson
Rob Simmons
Ben Tapuai
James O'Connor
Adam Thomsen
Sharks:
Willem Alberts
Ryan Kankowski
Francois Steyn
JP Pietersen
Ettienne Oosthuizen
Stormers:
Eben Etzebeth
Manuel Carizza
Frans Malherbe
Willy Ambaka
Kobus van Wyk
Siya Kolisi
Jaco Taute