When the finals begin you will have slightly more transfers allocated to you but fewer players to choose from - so, if you've loaded your team with Cheetahs, Reds or Blues players, then it's in your best interests to slowly ween them out of your squad over the coming three rounds.
To add to this conundrum, a string of major injuries have been announced over the past two weeks.
Bulls back-rower and fantasy star Jacques du Plessis is out for the season after breaking his jaw as is teammate Flip van der Merwe, Brumbies prop Stephen Moore and Reds halfback Will Genia.
Crusaders pair Richie McCaw and Israel Dagg will be sidelined for the near future, Brumbies lock Sam Carter is out for at least one round while Brumbies five-eighth Matt Toomua is out for two weeks.
Also out for the Crusaders is giant winger Nemani Nadolo who will turn out for Fiji this weekend.
Two players likely to receive reduced playing time are Chiefs stars Tim Nanai-Williams and Tawera Kerr-Barlow who have been named on the bench for their franchise.
Take a wait-and-see approach with returning players Dan Carter, Robbie Fruean, Francis Saili and Jackson Willison, while Kieran Read is not worth owning while the concussion cloud hangs over his head.
If you happen to have the luxury of exploiting matchups this weekend, look to Chiefs players Ben Tameifuna ($4,100,000), Liam Messam ($6,730,000) and Gareth Anscombe ($9,010,000).
Also with juicy match-ups are Rebels fullback Jason Woodward ($8,650,000), front rowers Corey Flynn ($4,130,000) and James Slipper ($3,860,000) and Force back rower Matt Hodgson ($4,610,000).
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Top pick
Jason Woodward, Rebels
Value pick
Matt Hodgson, Force
On the bench
Nemani Nadolo, Crusaders (international duty)
Jacques du Plessis, Bulls (out for season)
Richie McCaw, Crusaders (out 4 weeks)
Stephen Moore, Brumbies (out 2 weeks)
Matt Toomua, Brumbies (out 2 weeks)
Sam Carter, Brumbies (out 1-2 weeks)
Tim Nanai-Williams, Chiefs (benched)
Tawera Kerr-Barlow, Chiefs (benched)
Will Genia, Reds (out for season)
Flip van der Merwe, Bulls (out for season)
Israel Dagg, Crusaders (out 1-2 weeks)