For example, if you need to make more than four transfers to cover the missing players this weekend, then look to leave gaps in your side in the least-productive positions - halfbacks and front rowers.
You'll also want to keep in mind that the Sharks have a bye next week, so making any moves for their players this week may not provide the best value for your team.
If you have been smart enough to plan ahead for this round, then you'll have four or less transfers to make to field a full squad and this week will be like any other, where playing the matchups is key.
Number crunching
There are two fixtures that stand out as ones to target for fantasy points this weekend - Rebels v Brumbies and Blues v Highlanders.
The Highlanders concede the most fantasy points per game of any side, while the Blues are close behind in third place. Interestingly, the Highlanders also score the most fantasy points of any side - so, for me, they are the team to target.
According to the Herald Rugby Stats Centre, Ben Smith ($8,670,000) is leading the way for the southerners in metres-gained with 327m and is a good bet to score well on Saturday night. Teammates Malakai Fekitoa ($7,630,000) and Patrick Osborne ($7,610,000) are your value picks in that backline while back-rower Shane Christie ($3,630,000) could be the cheapest source of points in the entire round.
The Blues, likewise, can provide a number of great options for you - Luke Braid ($6,170,000) is averaging the sixth-most tackles per game, according to our stats centre, and will be an elite back row option again.
In the backs, Frank Halai ($8,590,000) and George Moala ($8,080,000) are solid investments while Charles Piutau ($8,080,000) is set for a big game against a Highlanders side that concedes the most metres-per-game in the competition.
Wizards of Oz
In Melbourne, the Rebels and Brumbies are likely to also provide a stack of fantasy points.
Players to target here are Brumbies backs Jesse Mogg ($9,600,000) and Robbie Coleman ($8,580,000), as well as Rebels back rower Scott Higginbotham ($5,130,000). Interestingly, Brumbies star Christian Lealifano is expected back from injury this weekend but will not be kicking goals, which mutes his value somewhat.
One final note to make is that our second chance competition starts from round nine.
All new players and existing players will be entered into a new competition from round nine to 22 with a chance to win a $5000 prize - so no matter how you're doing so far in the game, there is always a chance to take some money home.
Top picks:
Ben Smith, Highlanders
Charles Piutau, Blues
Value picks:
Shane Christie, Highlanders
Patrick Osborne, Highlanders
On the bench:
Israel Folau, Waratahs (out 1-2 weeks)
Patrick Lambie, Sharks (out for season)
Flip van der Merwe, Bulls (out 1-2 weeks)
Piri Weepu, Blues (out 4-6 weeks)
Cory Jane, Hurricanes (out 1-2 weeks)
Lachlan Mitchell, Rebels (out for season)
Liam Gill, Reds (out 3 weeks)
Schalk Burger, Stormers (out 1-2 weeks)
Ardie Savea, Hurricanes (benched)
Luke Burgess, Rebels (benched)
Sam Cane, Chiefs (benched)
Gareth Anscombe, Chiefs (benched)
Tim Nainai-Williams, Chiefs (benched)
James Parsons, Blues (benched)