Australia are on track for a one-day series whitewash over India after a 25-run win in Canberra on Wednesday.
The hosts set a tough target of 349 on a typically dry Manuka Oval pitch and backed it up with a nine-wicket haul for just 46 runs.
It was the first time in the series that Australia, who now hold a 4-0 lead, chose to bat first after winning the toss. It also marks their 18th straight ODI win at home.
Openers Aaron Finch and David Warner set the platform with a 187-run partnership, 107 of which was owed to Finch who racked up his seventh ODI century and first against India.
Warner, despite missing the previous two ODIs for the birth of his second daughter, was at his big-hitting best - smashing 93 off 92 balls before being bowled by Ishant Sharma.