Guptill hammered the Australians with a 90, 31 and 59 in the recent one-day series - but Hazlewood believes that golden patch will once again count for nothing.
"I think we did get the better of him in Australia. He plays a lot differently in Tests compared to one-dayers," says Hazlewood, who got Guptill out three times during the home series at the start of the summer.
"He's quite confident in limited-overs games - he knows his game really well at the top of the order.
"But I think he's still a bit uncertain in the Test arena so we'll be looking to exploit that again and stay on top of him as we've done in Australia."
The Aussies might not rate Guptill - but the opposite goes for the man it's his job to protect - New Zealand's ace No.3 Kane Williamson.
Kiwi captain-in-waiting Williamson didn't necessarily take off in the one-dayers - but Australia remember his dominance during the Test series at home earlier this summer and rate him as the No.1 wicket.
"I still think he's a better Test player than a one-day player. We have to get him out in Test cricket and I think the way we bowl to him in these last three (ODI) games has been pretty much spot on," he said.
"We've tried to tie him down and get him driving so that's going to be the key in these Test matches. He showed in Australia how good a player he is and I think he's got runs against every country in the world.
"He knows these conditions well so we've got to get on top of him early and try and get him early. I think he's that rock in their order that they feed off."
Aside from Guptill - the other New Zealander the Australians will be licking their lips at the sight of come Friday will be spinner Mark Craig.
The 28-year-old averaged a whopping 64.12 with the ball during the recent series on Australian soil - with his performances some of the worst ever seen by a spinner down under.
Teammate Tim Southee - making his comeback from injury - backed Craig to bounce back.
"Coming back to conditions he's familiar with, he would have learned a lot from that tour," said Southee. "As cricketers you're always trying to improve your game."
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