Nathan Lyon spun a patched-up Australian side closer to a 3-0 Test series sweep over Pakistan on day three of the SCG clash.
The tourists were 271-8 at stumps on Thursday, still trailing Australia by 267 runs despite a gallant century from Younis Khan.
Younis is 136 not out, having frustrated Steve Smith's side with the help of rain that washed out one and a half sessions in the morning.
Lyon grabbed three wickets on day three, including the key scalp of skipper Misbah-ul-Haq. Fellow tweaker Steve O'Keefe also helped Australia turn the screws, removing Asad Shafiq for four with the help of a remarkable slips catch from Smith.
Smith has been criticised by Shane Warne for much of the summer regarding his treatment of Lyon. The legendary legspinner had no complaints on Thursday when Lyon was called into the attack with the second new ball just five overs old.