"I will fight anybody, anywhere," he said. "I am going to fight probably before the election.
"The election is coming next year, May, and before that I will probably have one fight."
He added: "We are going to finalise by November or December."
Mayweather actually retired with a perfect record of 49 wins and no defeats following his last fight, a near shut-out points victory over the overmatched Andre Berto in September.
However, very few people in boxing circles actually believe the brash and controversial Mayweather won't fight again.
Any potential fight would take place in March or early April next year, said Pacquiao, who also told Qatari broadcaster Al Jazeera that it could take place in the Gulf.
Pacquiao has been widely regarded as second only to Mayweather in the theoretical pound-for-pound rankings over the last few years.
He has 57 wins, two draws and six losses on his record over a 20-year career.
The Filipino is in Qatar at the invitation of AIBA president, Ching-Kuo Wu, a personal friend.
Pacquiao, who lost to Mayweather in his last fight, said he was free from a shoulder injury he blamed for his defeat and which subsequently required surgery.
Now he insists he is ready for his next challenge.
He used to be a stable-mate of Khan's before the Briton switched camps, leaving the Freddie Roach Wild Card Boxing Club in Los Angeles to team up with Virgil Hunter at the King's Boxing Gym in Oakland.
Khan lost his last two fights while trained by Roach but under Hunter he has won five in a row, including a decision victory over American Chris Algieri - a former Pacquiao victim too - last time out in May.
Earlier on Thursday, Taz Khan, the uncle and manager of Amir, told AFP talks had begun with the Filipino's management team, but "at the moment that's all there is".
Amir Khan, who has tried unsuccessfully several times to arrange a fight with Mayweather, was keen for the Pacquiao bout to happen, said Taz.
"He's always up for any fight if it's on the table, he'll take it."
The British boxer is also expected to visit the championships at the weekend.
-AFP