He was ragdolled around the ring and stuck to the ropes as Fury dominated.
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The "Gypsy King" was feeling supremely confident and even dropped a moment that will go down in boxing history as Fury tasted blood in the water. Literally tasted blood.
Some social media fans have compared it to the Tyson ear bite on Evander Holyfield, but Fury appeared to lick the bloodied neck of Wilder as he clinched in the sixth round.
It may as well have been the kiss of death as the fight ended in the next round as Wilder's team threw in the towel.
But the moment erupted on social media as many people simply wondered "WTF?"
Others compared it to the Super Bowl halftime show when Shakira stuck her tongue out for no reason.
It's pretty clear it will soon become a meme.
Fury also celebrated, sticking his tongue out at the end of the fight as he was crowned the WBC World Champion, ending Wilder's 10 fight defence of the belt.
Fury is also The Ring and lineal heavyweight champion.
It sets up a potentially huge next fight with a reported rematch clause in the contract or a shot at unifying the heavyweight titles with a fight against countryman Anthony Joshua.
Wilder was furious after the result, slamming his team for throwing in the towel.
"My side threw in the towel, I was ready to go out on my shield," Wilder said.
"I had a lot of things going on coming into this fight. I make no excuse, I wish my corner let me go out on my shield. No excuses, I will come back and be stronger.
"Even the greatest lose, that's part of it. You take it for what it is. I had a lot of complications, we'll come back even stronger. This is what heavyweight boxing is all about."