"It is with great sadness and torment that we learned, from a representative of her family, that Jeanette Zacarias Zapata passed away this afternoon at 3:45pm. The entire team at Groupe Yvon Michel is extremely distressed by this painful announcement," Michel shared on Twitter.
"We would like to offer our most sincere condolences to her family, loved ones, friends and especially her husband, Jovianni Martinez, who was at her bedside until her last moments.
"Jovianni is devastated and extremely upset.
"Under the circumstances, he does not wish to comment, therefore we ask that you respect his decision and allow the family to have their privacy.
"In this painful period, you will understand Groupe Yvon Michel does not intend to comment further."
Following the news of Zapata's death, tributes have flooded in for the young welterweight as the boxing world comes to terms with the shocking loss.
A devastated Houle took to social media to pay tribute.
"I extend my deepest condolences to her family and spouse Jovanni Martinez," the message read.
"Thank you for respecting my desire not to comment more.
"The sad news of the departure of a great athlete like Jeanette Zacarias Zapata leaves me sad and devastated.
"I offer my sincere and deep condolences to her family and husband Jovanni Martinez.
"May God enlighten your soul and receive it in his glory."
Adonis Stevenson, the former WBC light heavyweight champion who had his career ended in a terrifying scenes against Oleksandr Gvozdyk in 2018 when he was placed in an induced coma, took to social media to share his condolences.
The World Boxing Council also paid tribute to Zapata.
"The president of the WBC, Mauricio Sulaimán and the entire boxing family affiliated with the WBC, as well as all boxing, mourns this irreparable loss.
"We send our deepest condolences to the family and friends of Jeanette. May she rest in peace."
The death is reportedly being investigated by the coroner in Quebec.
But UK-based brain injury association Headway released a statement calling for boxing to be banned after the latest death.
"It is impossible to imagine the grief being felt by the husband and family of such a young woman with her entire life ahead of her," Peter McCabe, chief executive of Headway, said in a statement. "Our thoughts go out to all who loved her.
"This tragedy was preventable. This precious life need not have been cut short."