"Floyd's favourite saying is 'It's going to be what it's going to be'," Mayweather's promoter Leonard Ellerbe said. "He knows in his mind that he's done everything he has needed to do."
Mayweather will be fighting for the 48th time in his pro career, while Pacquiao has been in 64 fights.
None of them, of course, have been paid so handsomely - Mayweather will make an estimated US$180 million ($238 million) and Pacquiao US$120 million - or been in a fight so anticipated.
"This is probably the most lonely hours they've ever had in their lives," said former heavyweight champion George Foreman. "There's no one truly to talk this over with. I remember how lonely it was for me and the bigger the fight, the greater the conversation you have with yourself. It's lonely - more than lonely."
Pacquiao, who is staying at a hotel just down the Las Vegas Strip from the MGM Grand arena, will have a Bible study session. He'll also go for a walk to get some fresh air, which could cause some consternation among tourists on the Strip who might see him passing by.
"It's pretty much a normal day," trainer Freddie Roach said. "But I don't like people to stay inside all day and get a little groggy."
Ellerbe said Mayweather will spend his day talking to members of his entourage and putting together the bag he brings his fight gear and other clothes in.
"He's a perfectionist with everything he does," Ellerbe said. "He's got everything planned out ... from socks to toothpaste to the suit he will wear after the fight."
Ellerbe said once Mayweather is ready to go, he might pick a car from his collection and drive to the arena himself.
"It's like he's going out to dinner somewhere. He'll drive 10-12 miles down the road, go in the ring and kick some behind, collect a cheque and go back to the house and have a party. He does it in that order."
Both fighters comfortably made weight yesterday as anticipation for their welterweight showdown grew.
The key pre-fight ritual drew a stunning crowd of 10,000 to the MGM Grand Garden Arena, where the rivals will clash this afternoon (NZT) in a fight that has catapulted boxing into the public consciousness in a way not seen for decades.
Tickets for the weigh-in were sold for US$10 apiece and some paid hundreds on the secondary market just for a chance to glimpse two of the most talented fighters of their generation.
Mayweather weighed in at 146 pounds (66.22kg) - one pound under the 147-pound (66.68kg) welterweight limit. Pacquiao weighed in at 145 pounds (65.77kg).
A galaxy of A-list celebrities will be ringside for a bout that has been debated and promoted on US television network chat shows.
Pacquiao's homeland of the Philippines is expected to grind to a halt as the impoverished nation of 100 million cheer their "National Fist" in open-air screenings, bars, cinemas and homes. For many Filipinos, Pacquiao embodies their hopes of escaping the poverty that affects one in four in the country.
His humble demeanour provides a compelling contrast to Mayweather, a brash self-promoter who glories in his status as a money-making machine and trails the clouds of a troubling past that includes jail time for one of several domestic violence incidents.
Pacquiao's good-guy reputation has made him the people's choice among punters in Las Vegas as well.
While Nevada's legal sports books are taking some big wagers on Mayweather, the money coming in from Pacquiao believers have narrowed the odds to about 2-1 in Mayweather's favour.
Public opinion is definitely with Pacquiao but boxing opinion is still Mayweather, most likely by a 12-round decision.
Mayweather brings a perfect 47-0 record to the bout along with a reputation for defensive skills that will thwart even aggressive south-paw Pacquiao.
Mayweather, a five-division world title-holder, has displayed an uncharacteristic ambivalence in the build-up to the fight.
"I never wanted to win a fight so bad in my life," he has said, at other times insisting facing Pacquiao is "just another fight".
Tune in to our live blog of the fight from 3pm on nzherald.co.nz/sport
- Agencies