The result was never in question as the OKC side put on one of their most complete performances of the season.
Taking a 33-25 lead after the first quarter, the Thunder saw the gap whittled down to six points at halftime.
Any hopes of a Lakers resurgence were snuffed out in the second half, as the Thunder outscored the visitors 54-36 in the final two periods of play to secure a well-deserved win.
The Thunder got production across the board, with all but one of their players who saw the floor putting the ball in the basket.
The side also followed Adams' lead on the offensive glass, as nine players secured at least one extra possession with an offensive rebound. The match was the third in a row in which at least seven Thunder players had collected an offensive rebound.
The result gives the Oklahoma City side a bit of momentum as they eye a clash with LeBron James and the Cleveland Cavaliers on Sunday.