Sebastian Coe insists athletics chiefs will intensify the war against drug cheats in the aftermath of the positive tests for Asafa Powell and Tyson Gay.
America's Gay, the fastest man in the world this year, and Jamaica's former world record holder Powell have both tested positive for banned substances.
It is not known which substance Gay took, although that should be confirmed after his B sample is analysed.
Powell, who has run 9.88secs this year but failed to make the Jamaican team for next month's Moscow world championships, was tested at the national trials in June and returned an adverse finding for oxilofrine - a stimulant that boosts fat-burning.
Jamaica's Sherone Simpson, a three-time Olympic medallist, also tested positive.