Auckland Transport road manager Andrew Bell said there were more people on the street on Friday nights compared with other days of the week.
"On Friday you have late-night pedestrians, particularly in the CBD there are drunk pedestrians and at night it's harder to see them," Bell said.
He said the number of fatalities and serious injuries involving young adults had increased during the last three years. However, the overall pedestrian casualties, including an alarming number of children, had decreased.
Living Streets Aotearoa president Andy Smith said people were more likely to be drunk or in a rush on Fridays.
"People are busy to get home or go on holiday in their cars."
Smith, who created the Eye See You campaign, said there needed to be better communication between drivers and pedestrians. "It's about making eye contact," Smith said.
Meanwhile, the statistics reveal the most dangerous road in Auckland is Great North Rd.
During the past three years, 14 people were killed or seriously injured on the busy road which runs through Grey Lynn, Pt Chevalier and Waterview.
Other dangerous roads include New North Rd and Victoria St West.
New Zealand Transport spokesman Andy Knackstedt said the Government spent about $200,000 this year to help improve the safety of pedestrians on Auckland streets.
A campaign aimed at pedestrian safety is expected to be launched by the NZTA, Auckland Transport, police and ACC in February.