Two people are in a critical condition and eight others are suffering from varying injuries following a crash involving multiple vehicles near Oamaru.
Police rushed to the scene on State Highway 1 at Maheno around 6pm to find people trapped in the vehicles involved.
At least three helicopters were sent to the incident.
Initial reports from police said five people were injured in the crash, later correcting that number to nine. However St John Ambulance confirmed 10 people had sustained injuries in the collision.