Emergency services have closed State Highway 5 near Tarawera following a major incident which saw a truck and trailer crash.
The road is likely to be closed for at least five hours following a diesel spill after the truck jack-knifed earlier today.
"The truck appears to have jack-knifed and crashed, blocking both lanes," police said.
"The driver of the truck suffered a medical event and is now in a serious condition in hospital.
"The road will be closed for at least five hours, as there is a large diesel spill across the road which will need to be cleared."