The female driver of a Nissan four wheel drive was taken to Tauranga Hospital in a serious but stable condition.
Acting Senior Sergeant Cam Anderson of Tauranga Police, the Western Bay area response manager, said it appeared the man's vehicle clipped a van travelling in the opposite direction.
''It clipped the vehicle and then impacted with the north-bound Nissan,'' said Mr Anderson.
"We were certainly stretched this afternoon and at least one staff member from Rotorua police was called on to help back us up," Campion said.
Emergency services were also called to a car crash at Cameron Rd and 21st Ave about 3.45pm.
It was understood a baby was taken to Tauranga Hospital.
Another crash backed up traffic at the intersection of Cameron Rd and 9th Ave ten minutes later.
So far this year, there have been 15 deaths on Western Bay roads.
The latest fatality comes just 15 days after Tauranga truckie Martin Ferry, 30, lost his life after a two-truck collision on the intersection of SH2 and Pongakawa Station Rd.
The road toll for the region last year was 18 deaths, while in 2014 there were 16 deaths on local roads and highways.
Bay of Plenty crashes this year
April 16: Cyclist Shinia Matehaere, 5, killed on Matapihi Rd after a collision with a ute.
May 7: Tauranga man Dion Pollero, 29, killed after his car collided with a truck on SH29 on the Kaimai Range.
May 21: Te Hira Whittaker-Ngaropo, 12, and his brother Chance, 16, died when their vehicle crashed on SH2 in Pikowai, near Pukehina.
July 29: Leigh Antoinette Rhodes, 60, and her friend Kenny McRae, killed after being struck by a vehicle while changing a tyre on Ms Rhodes' SUV on SH29A between Baypark and Maungatapu.
August 2: Tongan men Sitiveni Vaipulu, 44, Koli Vaipulu, 21, Halani Fine, 28, Samuela Taukatelata, 28, and Sione Teulaka, 21, killed after their car collided with a logging truck on the intersection of SH2 and Dawson Rd.
August 27: Respected Bay elder Paula Heke killed after her car collided with another vehicle on Te Puna Rd, next to the intersection of Te Puna Station Rd.
October 7: Tauranga father-of-two Shayne Peter Waaka, 40, after two car collision on SH29 Lower Kaimai Range.
October 13: Martin Ferry died in in a crash on State Highway 2 near Pongakawa.