State Highway 1 south of Taupō has reopened after a crash involving a logging truck.
Police were called to the crash at Waitahanui around 12.30pm.
Two people were in a moderate condition and one in a serious condition, police said in a statement.
A Hato Hone St John spokesman said two people with serious injuries were airlifted to Waikato Hospital and one person with moderate injuries was taken to Taupō Hospital by ambulance.