Then two men began smashing the car with what the witness believed was a rock and iron rod.
The person inside the car fled into a house.
Meanwhile, around 30 minutes after that incident, he said police detained a young man.
As they were doing so, another young man was crying and yelling at the detained man: "You killed my dad."
Another witness said 20-30 people had been restrained across two scenes, while they were questioned amid a heavy police presence of about 15-20 officers.
Counties Manukau CIB's acting Detective Inspector Karen Bright said police received numerous reports about the incident just before midday, after a man had been hit by a vehicle.
"The vehicle involved fled the area immediately afterwards. Emergency services attended the scene but sadly the man died shortly after."
Early reports suggested a firearm may have been involved in the incident and as a precaution, armed staff responded to the area.
Police had not located a firearm.
"Police immediately made inquiries in the Māngere area following the incident," Bright said.
Police on Wednesday afternoon were at an address near the scene where they were speaking to numerous people. No arrests have been made.
"Our investigation is still in the early stage and detectives will now work to piece together the full set of circumstances of what has occurred."
Police would like to hear from any witnesses to the incident or anyone who was on Thomas Rd at the time. They can contact police on 105 quoting the file number 210609/0607.
The incident, which occurred about 11.45am, forced nearby Thomas Rd and Jordan Rd to close.
The witness told the Herald armed police had also blocked an area of Pukaki Rd, which was about five minutes down Massey Rd from the scene of the suspected hit-and-run incident.
It is believed the hit-and-run took place on Thomas Rd while a separate incident occurred on Pukaki Rd.