British researchers have discovered a fast, accurate method of detecting deep vein thrombosis (DVT), potentially deadly blood clots that can develop during long-distance travel.
Unlike standard techniques that rely on monitoring blood flow to detect a blockage, the sophisticated scanning method - known as magnetic resonance direct thrombus imaging (MRDTI) - reveals the blood clot.
Scientists at the University of Nottingham who developed the method said it could be particularly helpful for pregnant women and travellers.
DVT has been dubbed "economy class syndrome" because of cramped conditions on airliners but experts say it can occur during any mode of transport after long periods of immobility.
"The great advantages that MRDTI has over other methods to detect thrombosis are that it is non-invasive, quick and reliable," says Professor Alan Moody, who led the research team.
Until now DVT has been detected by venography, in which a catheter is inserted into the veins, and ultrasound. The condition can be particularly difficult to diagnose during pregnancy if it originates in the pelvis, where it is hard to detect.
"MRDTI produces good images of the pelvis, and the pregnant mother would not need x-rays for us to see the blood vessels," said Professor Moody.
DVT can be fatal if the blood clot, or part of it, dislodges and moves to the lungs or brain.
Professor Moody said MRDTI was sensitive and allowed radiologists to diagnose and treat the condition at an early stage before symptoms such as leg pains developed.
In a study financed by the British Heart Foundation and published in the medical journal Annals of Internal Medicine, the Moody team tested the method on 101 people with suspected DVT.
A comparison of their results with standard tests confirmed its accuracy, the scientists said.
"We believe the future application of MRDTI will be enormously valuable in the early diagnosis and monitoring of DVT," said Professor Moody.
"This technology potentially could help protect people at risk of a life-threatening venous thrombosis as well as reassuring those who are not in danger."
The death of a 28-year-old woman from DVT after a flight from Australia to Britain in October 2000 made international headlines and raised awareness of the condition.
Most travellers' chances of developing DVT are thought to be quite low.
But passengers who are overweight or obese, are heavy drinkers or smokers or who have existing blood problems have an increased risk.
Airlines and doctors advise travellers on long-haul flights to exercise their legs, drink plenty of water and not to drink too much alcohol.
Below-the-knee compression stockings have also been shown to reduce the risk of DVT.
- REUTERS
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Scans will spot deadly blood clots much faster
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