Crown prosecutor Mark Williams told the jury police intercepted phone conversations and text messages, and used covert surveillance, to gather evidence between September 2009 and July 2010 of a well-organised drug-dealing enterprise.
Methamphetamine was often sold in ounce amounts (28.5 grams) commonly referred to as "an orange".
Mr Williams said Aenoy Bouavong, also known as Dion, was the leader of the particular group on trial, although he "may have danced to the tune" of others. His "trusted lieutenants" included his brother Phokam, Ka Kit "Derek" Poon and one Henry Mika.
In turn, multiple ounces of methamphetamine were supplied to Keophila and Nguyen. Each ounce was sold for $13,000 and Zhang, who worked for Dreamland Finance, helped launder profits by sending money overseas.
At Mika's arrest, police had found two ounces and more than $70,000 in cash. "That's the sort of money we're talking about," said Mr Williams.
The prosecutor said Bouavong also made "certain admissions" of drug dealing to police when he was arrested in July 2010 in a taped interview which would be shown to the jury.
He also said that a man with "direct knowledge" of the supply of pseudoephedrine - a Class-C drug which is the main ingredient of methamphetamine - would give evidence in the trial.
The witness, John Hsu, had been approached by a Daniel Hsu (no relation) and offered a job to pick up packages. John Hsu had been given a cellphone and texted an address to pick up a package from and another address to deliver the package to.
As well as thousands of tapped phone calls and text messages, a crucial piece of evidence is the "tick list" which allegedly belonged to Henry Mika - a handwritten ledger of supply and debt where transactions matched up with phoned or texted "orders".
All accused have pleaded not guilty except Aenoy Bouavong, who insisted on not entering a plea. The trial is set down for six weeks.