He said lung cancer was "the biggest cause of cancer-related death in this country and often it isn't diagnosed until it's too late to treat it".
Little said the medicines could be funded because the Government had increased Pharmac's budget to $1.1 billion.
He also alluded to the forthcoming consolidation of the health sector saying pairing research and drug purchasing showed what was possible with a linked-up public service.
"This is what a joined-up health service looks like – health agencies working together to identify problems and find and implement solutions," Little said.
The medicines included in the agreement include durvalumab for lung cancer, and benralizumab for severe eosinophilic asthma.
The agreement will also widen access to olaparib, a first-line treatment for some types of ovarian cancer and offer discounts on budesonide - the Symbiocort Tubuhaler for asthma and chronic obstructive pulmonary disease - fulvestrant, which treats a type of breast cancer, and gefitinib (for treating a type of cancer called epidermal growth factor receptor).