"More than 80 Police staff, including special groups such as the Armed Offenders Squad, Dog Section and Specialist Search Group, have been executing search warrants at seven properties throughout the Auckland region this morning.
"The warrants are part of the second termination phase of Operation Nova, an investigation into the gang, the alleged importing of drugs into the New Zealand and the laundering of millions of dollars."
Williams said a number of people have been arrested, including some senior members and associates of the Comanchero gang.
Assets valued at $3.7m had been seized.
"We are determined to strip them of that wealth that we allege has come from criminal offending, and take the profit out of it."
Detective Superintendent Iain Chapman, said the seizures would ensure that criminal wealth was not re-invested to help the gang grow.
"These seizures are also about removing the symbols of status and influence used by organised crime groups to attract others to join."
Regarded as Australia's most dangerous gang, numerous patched members have been deported across the Tasman by authorities.
"All done and sworn in ... welcome aboard to my brothers in New Zealand," said an Instagram post by an Australian member of the Comancheros last year.
"Another Comanchero chapter opened up. We growing stronger and stronger."
Read more:
• Australia's most dangerous gang opens New Zealand chapter
Members have been seen riding gold-plated bikes and New Zealand police said last year they were concerned about the gang's presence in this country.
The Comanchero are part of two of Australia's most infamous gang battles; the 1984 "Milperra Massacre" shooting with the rival Bandidos and the 2009 brawl at Sydney's international airport in which a Hells Angels member was beaten to death.