One person is in a serious condition and four others are injured after a crash in the Kauaeranga Valley, behind Thames.
Emergency services were called to the scene at 2.30pm.
A St John spokeswoman said one person had serious injuries, one had moderate injuries and three others had minor injuries.
All patients were taken to Thames Hospital.
A witness said they saw two St John rapid response vehicles, two police cars, a fire engine and an ambulance head up Kauaeranga Valley Rd.