A witness said a male was cut from a vehicle by firefighters.
About three or four vehicles stopped to help the driver, he said.
The driver had a neck brace on.
The motorway was "absolutely gridlocked" but the fast lane was open at the time and traffic had been moving slowly past the scene, he said.
Newstalk ZB caller Ian said he had been stuck in the traffic "for ages".
"We're moving really, really slow. There are cars for Africa here. It's bumper to bumper in every lane. If I heard [about the crash] on the radio earlier, I wouldn't have come this way."
A St John ambulance spokeswoman confirmed one person was in a critical condition and had been transported to Auckland City Hospital.
A person with minor injuries was assessed at the scene but no hospital treatment was required. A St John rapid response unit responded.
A police spokesperson said officers responded to reports of a vehicle collision on the Northwestern Motorway at 6.15pm. The police serious crash unit attended.
SH16 NORTHWESTERN MWY — 6:20PM A multi-vehicle crash is blocking eastbound lanes adjacent to the Rosebank Rd on-ramp on the #NorthwesternMwy. Emergency services are onsite, please slow down through the area and expect delays.^MF pic.twitter.com/m1joog09Zj
— Waka Kotahi NZTA Auckland & Northland (@WakaKotahiAkNth) July 12, 2021