Wellington City Council has reported a large slip outside the Karori tunnel, blocking the lane entering the suburb.
The council has advised contractors are on the way to assess the situation and motorists should use alternative routes.
It comes as the main route in and out of Wadestown has been kept closed this weekend, with heavy rain further threatening a landslide that's already come down twice.
The slip toppled onto Wadestown's Lennel Rd after wild weather lashed the region last week.
The conditions left a ferry stuck in the harbour for hours, tore the roof off a cafe in Lower Hutt, damaged vehicles, and grounded all flights in and out of the city.