"There aren't that many anti-malarial drugs out there and what are out there often have bad side-effects," she said.
"If the Earth is warming as they say it is, the malaria mosquitoes will start encroaching on the developed world and it's going to become rife. It's not necessarily a long time away."
Dr Pearce is one of only a handful of people working on anti-malarial medicine in New Zealand. Her findings are close to being tested.
The $180,000 she needs annually to continue her research comes largely from research grants and government funding, but such payouts are increasingly hard to secure.
"Unfortunately, New Zealand is quite small and there's not a heck of a lot of money around for research funding."
As well as using proceeds to fund her work, the sale of Shelly Beach Farm will allow Dr Pearce to spend more time with her husband.
Situated on the Kaipara Harbour, it is marketed as the country's first organic farm and includes 3km of coast and a private beach. Animals that come with the property include dairy and beef, cattle, emu and geese.
The property also has vines and a dung beetle breeding operation valued at several million dollars.
The beetles, which cost $1 each, bury dung dropped by animals, reducing greenhouse gases and environmental impact.
The multi-title property is being marketed by Bayleys. Two titles have a combined government valuation of $3.25 million, with further titles yet to be valued. Bayleys agent Karen Asquith said the government valuation was "not a guideline of current market value - it is light".
Dr Pearce has always had an interest in science and helping others.
She and her husband started the sustainable farm 33 years ago and university masters students live and work there as part of their studies.
APNZ