New Zealand researchers have found a new way to fight chronic lymphocytic leukaemia, a blood cancer that affects one in 400 Kiwis over the age of 70.
Haematologist Robert Weinkove of the Malaghan Institute of Medical Research said bone marrow transplantation was currently the only curative treatment for chronic lymphocytic leukaemia (CLL) and involved replacing the immune system of patients with that of a matched donor.
Such transplants can be problematic: not all patients find a donor; patients are prone to infections for months or even years afterwards; and the treatment can be so toxic that it is not suitable for many.
Dr Weinkove said that to identify lower-risk immune therapies, researches focused on a rare type of immune cell called "invariant natural killer T" (iNKT).
"Previous research at the Malaghan Institute and overseas has shown that iNKT cells can be activated by a compound called alpha-galactosylceramide (alpha-GalCer), which was first found in a Japanese marine sponge.