"I look forward to visiting the United States to meet with counterparts, and taking the opportunity to further promote New Zealand's reconnecting plan," Ardern said.
"It's an important opportunity to set out New Zealand's continued commitment to the multilateral system and international rules-based order. As the world continues to grapple with Covid-19, climate change, the Ukraine and geopolitical tensions, international co-operation is more important than ever," Ardern said.
While in the United States, she will co-host a Christchurch Call to Action Leaders' Summit, with French President Emmanuel Macron and participate in events to promote trade, investment, and tourism.
"I look forward to meeting with heads of state and global tech leaders to continue our important work to eliminate terrorist and violent extremist content online," Ardern said.
Leaders typically use UN General Assembly as an opportunity to meet one-on-one on the sidelines of the main event.
Ardern has a number of these planned, although she has not announced with whom she will be meeting.
She will also deliver New Zealand's national statement at the General Assembly.
Ardern will also meet with the Motion Picture Association of America, a trade body representing the film industry, to promote New Zealand as a film destination.
She will also attend the launch of the Invest New Zealand campaign "Do Good, Do Well" alongside major US investment funds.
Ardern said Air New Zealand's new direct flight to New York was "an exciting step in reconnecting New Zealand with the world, and will bring a welcome boost for our tourism and other businesses".