Both lanes of State Highway 1 south of Cambridge have re-opened since a head-on crash earlier today.
Northern fire communications shift manager Jaron Phillips says five people were injured in the 11.24am crash which happened on SH1 near Kentucky Rd, south of the SH29 turn off to Matamata and Tauranga, near Karapiro.
Two of the patients have serious injuries, one has moderate injuries and two others have minor injuries.
The road was initially blocked however emergency services were initially able to re-open one lane.
Waikato police Senior Sergeant Damian Rangitutia has confirmed both lanes were re-opened about 1.30pm and traffic is now flowing freely.