One person is seriously injured following a crash on State Highway 2, near Waipawa.
A police spokesperson said the crash involved a car and a truck, and occurred about 7.40am just south of the Waipawa Bridge.
A helicopter has been directed to the scene and motorists have been asked to avoid the area. The road was expected to re-open by 11.45am.
It is the second crash in the area in 48 hours, after a car and truck collided between Waipawa and Hastings on Saturday.