Drug squad detectives are investigating any link between pills which put six Hamilton girls in hospital and an alleged criminal syndicate in Auckland which made tens of thousands of designer drug tablets each week.
The Fairfield College pupils, as young as 13, swallowed the pink pills at school, which led them to react aggressively when admitted to Waikato Hospital's emergency department.
Health professionals believe the abusive behaviour - inconsistent with Ecstasy use - was caused by man-made chemicals such as mephedrone mixed into Ecstasy tablets.
And mephedrone is among the chemicals allegedly mixed into tens of thousands of pills each week by a drug ring busted by police last week.
Detective Inspector Bruce Good, head of the Auckland metro drug squad, confirmed he had contacted police colleagues in the Waikato after the schoolgirl scare on Monday.