The producer denies all allegations of non-consensual sex, though he admits inappropriate conduct.
Weinstein is an extremely well-connected liberal US figure. A longtime Democratic donor, he hosted a fund-raiser for Hillary Clinton last year, employed Malia Obama, the oldest daughter of former President Barack Obama, as an intern and helped endow a university chair in Gloria Steinem's name.
When the Sundance Film Festival held its version of nationwide women's marches Weinstein joined the parade.
For a brief time Weinstein adopted a defence of repentence, claiming through his lawyer that he belonged to an age when workplace rules appently permitted abusive behaviour. He also declared he was getting help for his compulsions.
Essentially he was pitching for a second chance. That option seems no longer available. The sheer scale of allegations has destroyed his reputation, and the powerful company he ran has fired him.
New Zealander Zoe Brock, a former model who was among the Weinstein accusers, challenged male celebrities to speak out.
"I'd love to hear from some of those guys," Brock said. "They are all men I admire and look up to as artists. They're all men with daughters. It's horrifying."
It has taken a while but some of Hollywood's biggest stars finally have stepped up, even though some were outspoken in their criticism of Donald Trump when accusations of sexual misconduct surfaced in the presidential campaign.
The film industry of course in hardly the only place that shelters abusers or buries the fact that powerful men sometimes exploit their dominant status.
In this country New Zealand Rugby was forced to address bad behaviour after a series of unsavoury incidents.
A common theme in these events is the exploitation of young vulnerable woman afraid their careers could suffer by saying no.
The simplest thing men could do when they know workplace abuse is occurring is speak up. The silence around Weinstein allowed him licence to allegedly behave for decades in ways that could yet see him face criminal charges.
For women to know they have the support of men against their abusers could make a huge difference.
And it does men no harm to see other men step forward when the easiest thing is to do nothing at all.
