Several other members of the executive leadership team have resigned since July this year.
Board chairman Sir John Hansen said through his various roles in health and management. Bramley has managed a wide range of challenging scenarios and has a proven track record in bringing about large-scale transformation.
"His reputation is as a people person, who can support and enable others to achieve great things. During his time with us as acting chief executive he proved his relationship management skills and worked positively with all stakeholders from throughout the health system. He has strong networks and familiarity with the sector.
"Importantly, Peter is aware of our financial situation and knows there are plenty of challenges and opportunities ahead," Hansen.
Bramley said he looked forward to moving to Canterbury and starting the new role.
"I enjoyed my time in Canterbury and on the Coast and know I'm going to be responsible for two very different DHBs – both have a wealth of talent, and both have complex, but different challenges. With fantastic teams to work with on both sides of the alps, I know we can achieve great things."