"The numbers … suggest that the vaccination effort has run into firm resistance in the last 10 per cent to 20 per cent of Māori," Taonui said.
"The lower uptake of first and second vaccinations reflects a final wall of resistance.
"As Omicron builds, the largest risks lie in high Māori demographic, high impoverishment, and remote areas."
Home isolation was a major risk for Māori, he said.
"In the urban centres, the sheer number of Māori cases will shape the risk, meaning some whānau may not receive vital support. In rural areas, the risk lies with living at distance from medical care."
In the Whanganui District Health Board region, the Māori vaccination rate has barely shifted in two weeks, with 87.2 per cent of eligible Māori getting their first shot and 83.3 per cent double vaccinated. That is a difference of 0.2 and 0.3 per cent from two weeks ago.
More than 400 first jabs are needed for Māori in the region to reach the Government's 90 per cent target, and about 1000 vaccinations will hit the double vaccination milestone.
Taonui said Māori are still well behind the national rate for boosters, but the gap is closing. Since early February when the Government reduced the wait for a booster from four to three months, Māori booster uptake had jumped by 53.8 per cent.
"The vaccinated majority is pursuing booster vaccinations at a high rate," Taonui said.
But he warned that Covid-related protests in Wellington and other centres would spread the virus.
"There is no doubt that several of the current so-called Freedom camp-ins around the country will become super-spreader events. When they return home, they will take Omicron with them."
Taonui said the anti-vax movement has a parallel in New Zealand history.
"Between 1800 and 1915, there was a significant anti-vax community in New Zealand. Much of their focus was on the smallpox vaccine. Anti-vaxxers spread misinformation that the vaccination caused leprosy, other diseases and death and that it was a plot against the freedoms of the population."
Previously high Māori smallpox vaccination rates fell away.
"Many Māori, mistrustful of the government after the Pākehā wars on Māori and the taking of Māori land, supported the anti-vax sentiment," Taonui said.
"In 1913, a recently arrived American missionary infected several Māori at a gathering in Northland. When the delegations returned home, they took the infection with them."
More than 200 Māori died, Taonui said.
