National organised crime group national manager Detective Superintendent Greg Williams said nearly 50 firearms were seized in total, and more than 90 people were arrested.
"New Zealand Police continues to hold organised criminals accountable even through this challenging time," he said.
"The illicit activities these groups take part in cause immeasurable harm in our communities."
Nationwide, 25kg of methamphetamine and 30kg of cannabis, plus small amounts of cocaine, MDMA, gamma-Butyrolactone and LSD were all seized.
In the South, raids included the arrest of an alleged cannabis dealer in Alexandra, a Dunedin raid that netted $40,000 in cash and methamphetamine, and a Queenstown bust that turned up methamphetamine, cash and four firearms.
Staff across the country had been policing in a changed environment and had observed all health and safety requirements, Williams said.
The recovery of criminal proceeds also continued throughout alert levels 3 and 4.
More than $4.4 million had been forfeited, most of which related to drug crime.
In addition, more than $2m had been restrained and would be subject to further investigation pending forfeiture.