Forget the menopause. It may have been branded the "great taboo" by Britain's chief medical officer, who this week urged more open discussion of it between bosses and female workers, but for many middle-aged women the "change of life" does not, perhaps, top their list of worries.
Of greater concern is not finding work at all. For a growing number of highly qualified, professional women in their 40s and 50s are struggling to get into the job market.
Many have taken career breaks to look after children or elderly parents. Others have simply struggled to find a new job at their stage of life. All risk becoming what has become known, in bitterly colloquial terms, as "finished at 50".
Last year, figures from Britain's Office for National Statistics revealed there were 162,000 unemployed women over 50 - a 45 per cent rise since 2010, and the highest number since the ONS began collecting such data in 1992.