If the mere thought of fingernails scraping along a blackboard makes you cringe, blame your amygdala.
Scientists have discovered that this primitive almond-shaped brain region is behind our aversion to high-pitched sounds.
They say our reaction to the sound of scraping nails - which is in the same frequency range as screams and babies cries - could be an ancient survival instinct.
The study scanned the brains of 13 volunteers while they listened to a range of sounds before rating how much they liked them.
The more unpleasant a sound, the greater the amygdala - one of the first brain structures to evolve - lit up. It then activated the auditory cortex, which processes sound, leading the volunteers to perceive the noise more keenly.