It suggested they were gender fluid because they wear each other's clothes, but the headline got many Twitter users riled.
"Gigi Hadid and Zayn Malik Are Part of a New Generation Embracing Gender Fluidity," it read, and the Twitterverse was quick to react.
"Think @Vogue is a bit confused on what gender fluidity is! Wearing your gf's T-shirt does not make you gender fluid," one wrote.
"Vogue talking about gender fluidity: cool! Vogue talking about gender fluidity with a hetero couple that borrows each other's t-shirts: LOL," another chimed.
"Zayn and Gigi are profiled in this piece on gender fluidity because... they borrow each other's clothes sometimes?" a confused third tweeted.
"Ahm, I like Zayn and Gigi, I appreciate and respect them. However what does 'them sharing clothes' has to do with them being gender fluid?" another asked.
"Where is Zayn's skirt?" another irate user demanded. "And even tho an outfit define the gender's fluidity of someone?"
Some however were quick to defend the couple, insisting the headline was not their words.
"Zayn didn't say he was gender fluid. he said that CLOTHING HAS NO GENDER," one fan insisted. "Stop being fake woke and learn before you look foolish."
In the issue the two - who call New York City home base - talked about wearing each other's clothing. He admitted to borrowing an Anna Suit shirt while she said he "shops in his closet."
"It's not about gender. It's about, like, shapes. And what feels good on you that day. And anyway, it's fun to experiment," said the former Guess model.
"One day you can be this," she says.
It's noted that Malik is wearing a bedazzled Gucci blazer.
"And another day you can do that," she adds.
"If Zayn's wearing a tight shirt and tight jeans and a big, drapey coat. I mean-I'd wear that, too. It's just about, Do the clothes feel right on you?' said the blonde beauty.
The Vogue writer then added that Malik "shoots Hadid a tender look" and joins the conversation.
"With social media, the world's gotten very small and it can seem like everyone's doing the same thing. Gender, whatever-you want to make your own statement. You know? You want to feel distinct," the Pillow Talk hit maker said.
In the article, Vogue states: "The line that has long stood between a man and a woman's wardrobe has been slowly disappearing over the last few years. Right now a genderquake is taking root on the runway, and this month's Vogue cover stars are part of a new generation embracing the idea with open arms."
The August issue of Vogue is out on July 25.