The Sun took the subject a step further on Monday night (NZT) in the lead story on its website, which was headlined: "Meg claims Royals' concerns over Archie's 'dark skin' meant he wasn't prince".
Over in the non-tabloid zone of British media, Meghan's mental health crisis and racism claims also took centre stage.
The Daily Telegraph's website led with a large image of the Sussexes and the headline: "Royal family accused of racism as Duchess reveals suicidal thoughts".
Other stories at the top of the site covered Meghan's claim that Kate made her cry, Harry's revelation that his dad stopped taking his phone calls, and the fact the pair had a "secret wedding" days before the one the whole world saw.
The Guardian published a relatively restrained four Meghan and Harry stories at the top of its website on Monday night, leading with this headline: 'I didn't want to be alive any more' / Meghan and Harry describe racism and royal animosity in Oprah interview'.
The Independent also took a comparatively low-key approach, leading its website with the headline: Harry 'let down' by Charles as Meghan says she had suicidal thoughts', followed by four breakout stories (Archie's skin; suicidal thoughts; baby gender reveal; Charles ignoring Harry's calls).
Meanwhile, controversial media commentator and predictable Meghan slammer Piers Morgan piped up with this via Twitter: "I wouldn't believe Meghan Markle if she gave me a weather report."
He also accused Harry of wanting America and the rest of the world "to hate his own family, hate the Monarchy and hate his country".
As the UK wakes up to Meghan and Harry's interview, BBC royal correspondent Jonny Dymond said one specific part signalled a "worst-case scenario" for the palace.
That part, to nobody's surprise, is the alleged conversations with Harry about the colour of Archie's skin.
"The allegation ... is a devastating one," he said.
• CBS presents Oprah with Meghan and Harry will broadcast on Three on Tuesday, March 9, at 7.30pm.
