Giving oxygen to heart attack victims may do more harm than good, a study suggests.
Ambulance Victoria treated 440 patients - half of whom were given oxygen, with the other half breathing normal air.
The study found heart attack victims treated with oxygen endured more heart damage than patients not given oxygen.
For decades it has been routine practice to treat heart attacks with oxygen.
"This study is likely to change the practice of ambulance services in Australia and around the world," Ambulance Victoria paramedic and research co-ordinator Ziad Nehme said on Thursday.