"This generation realised that this is an accessory," she said from her office in the US.
"It's woven in to our social conscience now.
"It's affordable, you can change it as often as you like, there's no big commitment.
"I really don't see it slowing down."
Weiss-Fischmann co-founded the brand in 1989, taking it from a dental supplier called Odontorium Products Inc, to the internationally renowned OPI, boasting more than 1500 different shades.
"We really made nail polish sexy, we made it fun, we gave it names, we really appealed to the emotional psyche of a woman. We took her travelling, we made her remember the colours, they became meaningful."
Weiss-Fischmann tries to come up with at least half a dozen new collections each year, including seasonal looks inspired by catwalk trends and her travels.
"The way I really do this - I look at trends, trend predictions out of Milan and Paris which are usually a couple of years out, you kind of see different fabrics, textures, colours that will be important, what society is looking for, what's trending - whether it's modern and linear or you are going back to nature. All those things influence the colour choices that I make for a collection," she says.
"I just sit in a cafe and watch people. Everything influences me. The music, the people. I always say the average woman is my muse."
Weiss-Fischmann is never seen without a lick of colour on her nails. At the moment each finger is painted with a different bright shade as she experiments with the latest looks for spring/summer 2012, inspired by Holland. She says oranges and corals are still in favour, glitter is going gangbusters and nail art is going to continue to boom.
The brand also collaborates with celebrities (Nicki Minaj, Nicole Richie) and films (first Legally Blonde and most recently The Muppets). Later this year OPI will launch six sheer shades inspired by the New York City Ballet and the next movie collaboration will be a series of brights tied in with the new Spiderman flick, Weiss-Fischmann said.
OPI are known for coming up with quirky names - My Chihuahua Bites (an orange red from the Mexico collection) is one the most popular, Up the Amazon Without A Paddle (a shimmery orange red from the Brazil collection) is one of Weiss-Fischmann's favourites and I Have a Herring Problem (a shimmery blue) is one she came up with for the new Holland collection "because I happen to love herring, I'm one of the few people".
Other geographically inspired names include A True Ab-Original (a gleaming coral from the Australia collection), Aphrodite's Pink Nightie (a frosty pale pink from the Greece collection) and Austin-tatious Turquoise (a bold blue green from the Texas collection).
Meanwhile, in the most recent range to hit Kiwi shelves, The Muppets movie inspired Gettin Miss Piggy With It (a glitter-laced ruby red), Warm and Fozzie (a honey bronze) and Animal-istic (a shiny, pink red).
So will the OPI paintbox ever run out of colours?
"People ask me how I make a new red. I say, 'like I've never made a red before'.
"How can I have six pairs of black pants in my closet? They're all different."
Check out our gallery of the most popular OPI shades in NZ. What's your favourite?
