The line includes a vintage Led Zeppelin and Pink Floyd tee with two huge "K" letters plastered over it.
None other than Biggie Smalls' mother, Voletta Wallace, has slammed the designs featuring her late son's image, saying: "The disrespect of of these girls to not even reach out to me or anyone connected to the estate baffles me. She labelled the t-shirts "disrespectful, disgusting and exploitation at its worst."
Both Jenner sisters tweeted out a hasty apology in the wake of the backlash, announcing that they would be pulling the t-shirt line from sale immediately and making special apology to the families of the artists whose images they'd used.
Earlier, Instagram photos promoting the designs on the Kendall + Kylie account were flooded with comments from less-than-impressed followers.
One user suggested, "with all the money these girls make you'd think they'd hire people with original ideas, and plastering your faces on top of legends!?!?"
Another noted that the designs were "so unbelievably disrespectful to every one of the musicians that you decided to plaster your faces on their logos/pictures".
An angry follower accused the famous pair of "defacing" the original band tees, and inquired, "Seriously do you even know a single KISS song??"
But that hasn't deterred some fans from buying the tees, which social media users blasted as "overpriced".
At least two of the designs available on kendall-kylie.com were marked as being "low stock".
Kendall and Kylie's fashion line has previously received favourable reviews from influential style publications, including American Vogue.
"There were other zeitgeist-y pieces - puffy bombers, tear-away pants, "naked boots" - but the liquid-silk slip dresses in rust and olive lent a dose of sophistication to the line-up," vogue.com wrote of their fall 2017 read-to-wear collection.
Vogue also praised the sisters for a "particularly inventive hooded velour bodysuit".
The Keeping Up With the Kardashians stars have previously been accused of copying other designers.