The fact that it was continually being used for purposes for which it was not originally intended just fuelled the animosity felt towards it.
Graphic designers, for whom matching typeface to tone and content of message is a key tenet, are especially offended by transgressions of this nature. Why, they ask, would someone use such an informal and childish font on any serious communication?
The story goes that Comic Sans MS was inspired by the lettering in comic books and therefore its right and proper home is inside speech bubbles.
According to the purists, while it may be used on children's birthday invitations, it categorically should not be used on curriculum vitae, menus, business documents, medical or technical literature, the sides of ambulances or for sign-writing of any kind.
It's a font that's unashamedly informal and upbeat but now the very attributes that made it successful are considered flaws.
People complain about its "faux joviality" and call it "pedestrian and tacky".
It's the subject of a joke: "Comic Sans walks into a pub and the bartender says, 'We don't serve your type in here'."
Graphic designers Holly and Dave Combs were so incensed they started a movement at bancomicsans.com while comicsanscriminal.com is dedicated to "helping people like you learn to use Comic Sans appropriately".
Those in the Twitter-sphere are all too familiar with its failings. In August alone there was a diverse variety of views expressed about this much-maligned font.
Nancy Knight, Baltimore: "First they mess up the Election Day date on the sample ballot. Now the Board of Elections sends a correction printed in Comic Sans. Wow."
Oskar Sundberg, Amsterdam: "my art director colleague just wrote and signed his resignation letter in comic sans. with colours."
Chris Gatewood, video director: "Sometimes when I'm alone, I use Comic Sans."
I suspect that few people are genuinely offended by the injudicious use of this font; for most it's probably no more than a source of mild annoyance.
The allure of being part of this 'in joke' is no doubt entwined with the opportunity it provides to raise a superior eyebrow at those who use it inappropriately. It affords the chance to bond with like-minded souls and to sneer at anyone not cognisant of its place in popular culture.
Of course, all it will take is for one of those superior sneerers to begin using it in a quietly ironic way for the line to be blurred between those in the loop and those out of it. Talk about complicated.
But whether you love it, hate it or are ironically attached to it, you have to admit that this typeface has well and truly made its mark.
Comic Sans MS: it's the little font that could.